Sildenafil Vs Tadalafil: How Are They Different And Which One Is Better?

According to the Urology Care Foundation, about 30 million men in America only experience problems with getting or maintaining an erection.

When men experience some form of erectile dysfunction they turn to oral medications such as tadalafil and sildenafil, these medications temporarily address the problem. Even though these medications have the same action mechanism, there are some key differences. For example, a widely used medication called Bluechew can have both sildenafil and tadalafil options.

In this tadalafil vs sildenafil blog, we will discuss some differences to help you choose the right drug to treat ED.

How Do These Drugs Work?

Tadalafil and Sildenafil are both classified as phosphodiesterase type 5 (PDE5) inhibitors. They are used for the treatment of erectile dysfunction. The PDE5 inhibitors work only during sexual arousal. The PDE5 inhibitors rely on a naturally released chemical called nitric oxide (NO) and it is only released during sexual stimulation. The interaction of PDE5 and nitric oxide activates guanylate cyclase and converts into cyclic guanosine monophosphate (cGMP). The collection of cGMP in the body results in the relaxation of blood vessels inside the penis. It increases the blood flow to the penis and increases the blood flow to the penis to help maintain and get an erection. 

Which Drugs Last Longer? 

Sildenafil was first approved by the FDA to treat erectile dysfunction on March 27th, 1998. Sildenafil became the first oral drug to be approved by the FDA. tadalafil was approved for the treatment of ED on November 21st, 2003. Tadalafil is the third PDE5 inhibitor approved drug sold on the market. 

Tadalafil has an advantage over sildenafil- tadalafil lasts longer. Sildenafil is usually effective for 4 hours, while tadalafil lasts for 36 hours. If you take tadalafil on Monday evening, you can count on your erection through Wednesday. With tadalafil, there will be no fear of running out of time and you won’t have to stay on your toes, you can have sex whenever you wish. So if you are into sexual spontaneity, tadalafil is the right drug for you. 

What Is The Usual Dosage Of Tadalafil And Sildenafil? 

Tadalafil is safe to take daily or as needed. Tadalafil is used in smaller doses. Usually, 10mg is the starting dose and is taken before sexual activity. The dosage may be increased if 10 mg is not as effective and the dodge can also be reduced if the adverse effects are severe. Sildenafil, on the contrary, is taken when needed at a dose of 50mg approximately 1 hour before sexual activity. The dose can be increased if 50mg is ineffective and if there are no side effects. Sildenafil should only be taken once a day even. 

What Are The Side Effects of Tadalafil And Sildenafil? 

Side Effects of Tadalafil: 

The most common side effects of Tadalafil are:

  • Headaches
  • Nausea
  • Stomach Problem
  • Flu-like symptoms 
  • Blurred vision
  • Low blood pressure
  • Priapism 

Side Effects Of Sildenafil:

About 15% of the population taking sildenafil experience side effects. The most common side effects are:

  • Facial Flushing
  • Headache
  • Dizziness during sex 
  • Nausea 
  • Rash 
  • UTIs

Leave a Reply